Advanced In Vivo Systems for Next-Gen Biological Insights
Reliable, sensor-powered in vitro platforms enabling scalable, high-fidelity cell-based experimentation and predictive modeling.
Biological Insights through In Vivo System (IVS)
In vivo systems are essential platforms that enable scientists and researchers to simulate biological processes outside of living organisms. These systems replicate cellular environments with high accuracy, offering invaluable insights into drug response, toxicology, gene expression, and cell signaling. Unlike in vivo studies, IVS allows for tightly controlled experimental variables and real-time monitoring in a reproducible, cost-effective manner.
By integrating advanced sensors and AI-enhanced analyzers, modern IVS solutions facilitate predictive biology, reducing the need for animal testing and accelerating early-stage research. These systems are vital for applications across biotechnology, pharmaceuticals, healthcare, and life sciences.Physi Analytica, based in North America, is a B2B company committed to providing high-performance, hardware-based solutions. With cutting-edge technology and exceptional customer support, we empower laboratories and institutions to perform robust, scalable research using state-of-the-art in vitro systems.
Technological Core: High-Precision Hardware for IVS
In addition to offering products and systems developed by our team and trusted partners for In Vivo System, we are proud to carry top-tier technologies from Global Advanced Operations Tek Inc. (GAO Tek Inc.) and Global Advanced Operations RFID Inc. (GAO RFID Inc.). These reliable, high-quality products and systems enhance our ability to deliver comprehensive technologies, integrations, and services you can trust. Where relevant, we have provided direct links to select products and systems from GAO Tek Inc. And GAO RFID Inc.
Hardware
- High-precision sensors (optical, electrochemical, infrared): Enable real-time detection of cellular changes and analyte concentrations.Optical & Imaging Sensors Ideal for AI-enhanced analyzers used in IVS-based fluorescence and absorbance assays.
- Embedded processors with AI chipsets: Facilitate real-time data analysis and adaptive control of in vitro environments.Device Edge Supports intelligent, localized computation for cell-based assay platforms.
- Modular housings for environmental protection: Designed to maintain sterile, temperature-controlled environments for prolonged culture experiments.Environmental & Agriculture Sensors Integrated in modular enclosures for responsive micro-environmental monitoring.
- Data acquisition modules and built-in calibration features: Deliver high-resolution data tracking, improving the repeatability and reliability of results. Industrial & Asset Monitoring Sensors Support precision calibration and system diagnostics for in vitro sensors.
- Wireless and Ethernet-enabled communication ports: Provide seamless data transfer, control, and automation capabilities. Wi-Fi HaLow End Devices Enable long-range, low-power connectivity between IVS units and remote data systems.
Software
- Intuitive interfaces for real-time data acquisition and visualization
- Automated scheduling of experimental workflows
- AI-based analysis tools for signal detection and predictive modeling
- Batch data processing modules for high-throughput studies
- Integration with electronic lab notebooks (ELN) and lab information systems (LIS)
- Customizable alert and notification systems for anomaly detection
Cloud Services
- Secure, remote access to system dashboards and controls
- Real-time experiment monitoring and logging across multiple locations
- Centralized cloud storage with backup and redundancy
- Encrypted data transmission and cloud-based disaster recovery
- Integration with existing cloud infrastructures (e.g., AWS, Azure)
- Regulatory-compliant cloud infrastructure (FDA 21 CFR Part 11, HIPAA-ready)
- Multi-tenant architecture with secure sandboxing
Key Features and Functionalities
- Real-time cellular monitoring using optical, electrochemical, or impedance-based sensors
- Dynamic environmental control (e.g., pH, oxygen, CO₂, temperature)
- Scalable platforms for high-throughput screening or single-well analysis
- Automated dosing and media exchange integration
- Predictive analytics compatibility for preclinical modeling
- Minimal sample volume requirements and high detection sensitivity
- Maintenance-free operation with remote diagnostics and low drift calibration
Integrations and Compatibility
- Compatible with automated liquid handling system
- Interfaces seamlessly with fluorescence microscopes, plate readers, and spectrophotometers
- Integrates with lab information systems (LIS) for secure data logging
- Compatible with most industry-grade modular incubators and biosafety cabinets
Benefits
- Eliminates ethical and logistical constraints of animal testing
- Enables faster drug screening and toxicity profiling
- Provides reproducible data under tightly controlled conditions
- Reduces experimental variability
- Decreases overall R&D costs
- Accelerates time-to-market for biopharma development
- Enables custom, patient-specific therapeutic studies
Applications
- Drug discovery & lead optimization
- Toxicology & safety pharmacology
- Stem cell research & regenerative medicine
- Gene editing and CRISPR-based validation
- Infectious disease modeling
- Cancer biology & tumor microenvironment studies
- Nutraceutical and cosmetic efficacy testing
Industries Served
- Pharmaceutical R&D
- Biotechnology
- Clinical laboratories
- Academic research institutions
- Regulatory agencies
- Life sciences startups
- Personalized medicine labs
Relevant U.S. & Canadian Standards
- FDA 21 CFR Part 58 – Good Laboratory Practice (GLP)
- OECD Guidelines for Testing of Chemicals
- USP <1032>, <1033>, <1034> – Biological Assay Validation
- ISO 10993 – Biological Evaluation of Medical Devices
- Canadian Biosafety Standards (CBS), 2nd Edition
Case Studies
USA Cancer Drug Screening with IVS in San Diego, CA
A biotech startup leveraged Physi Analytica’ IVS solution embedded with AI-powered imaging sensors for high-throughput screening of oncology compounds. Results matched 94% of subsequent in vivo findings, significantly cutting preclinical study duration and reducing animal testing by over 60%.
USA Neurotoxicity Testing in Cambridge, MA
A leading pharmaceutical R&D firm deployed our modular IVS platform integrated with Wi-Fi HaLow end devices to assess neurotoxic effects of CNS-targeting drug candidates. The system enabled real-time cell impedance monitoring, delivering fast, reproducible outcomes aligned with FDA validation requirements.
Canada Stem Cell Differentiation in Toronto, ON
A Canadian academic research center used our in vitro platform equipped with Environmental & Agriculture Sensors to monitor temperature and gas levels during stem cell differentiation. The project improved process efficiency by 45% and demonstrated significant reproducibility across trials.
Contact Us
For more information about our In Vivo Systems, product compatibility, or to request a consultation, reach out to us.
We’re ready to help you implement scalable, precise, and innovative in vitro solutions tailored to your application.