Advanced Seahorse XF Analyzer Solutions for Real-Time Cellular Metabolism

Explore precision-engineered Seahorse XF analyzer systems tailored for metabolic research, drug discovery, and real-time cell analysis.

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Seahorse XF Analyzer: Real-Time Metabolic Profiling for Live-Cell Bioenergetics

The Seahorse XF analyzer is a cutting-edge bioanalytical instrument that measures cellular metabolism in real-time by analyzing oxygen consumption rate (OCR) and extracellular acidification rate (ECAR). These parameters provide critical insights into mitochondrial respiration and glycolysis, enabling a deeper understanding of cellular bioenergetics, disease progression, and therapeutic responses.

Ideal for live-cell analysis in microplate formats, the Seahorse XF platform is widely used in drug discovery, cancer biology, immunology, and metabolic disease research. It offers dynamic, non-invasive measurements in physiologically relevant conditions, without requiring cell labeling or lysis.Physi Analytica delivers a comprehensive portfolio of Seahorse XF technologies, customized for B2B research facilities across North America. With robust instrumentation, reliable integrations, and expert-backed support, we empower laboratories to extract meaningful metabolic insights with accuracy and speed.

Core Components of Seahorse XF Analyzer Systems

In addition to offering products and systems developed by our team and trusted partners for Seahorse XF analyzer, we are proud to carry top-tier technologies from Global Advanced Operations Tek Inc. (GAO Tek Inc.) and Global Advanced Operations RFID Inc. (GAO RFID Inc.). These reliable, high-quality products and systems enhance our ability to deliver comprehensive technologies, integrations, and services you can trust. Where relevant, we have provided direct links to select products and systems from GAO Tek Inc. And GAO RFID Inc.

  • High-precision sensors (optical, electrochemical, infrared)
    Our Optical & Imaging Sensors enable ultra-sensitive detection in Seahorse XF Analyzers by capturing real-time cellular metabolic shifts with precision.
  • Embedded processors with AI chipsets
     Integrated Device Edge solutions support advanced local processing for rapid metabolic flux analysis and AI-driven insights in Seahorse XF platforms.
  • Modular housings for environmental protection
    Rugged Industrial & Asset Monitoring Sensors enhance environmental control in Seahorse XF systems, maintaining optimal assay conditions across diverse lab setups.
  • Data acquisition modules and built-in calibration features
    Us Temperature & Process Calibrators ensure consistent calibration and data integrity for accurate real-time metabolic readouts in Seahorse XF Analyzers.
  • Wireless and Ethernet-enabled communication ports
    Seamless integration with LoRaWAN Gateways enables long-range wireless connectivity for decentralized Seahorse XF Analyzer deployments across research environments.
  • Seahorse Wave Data Analysis Software
  • Real-time metabolic flux mapping modules
  • OCR/ECAR profile comparison tools
  • Time-based curve fitting and statistical reports
  • 21 CFR Part 11-compliant audit trail functions
  • Export and integration-ready APIs
  • Remote access to live and historical assay data
  • Cloud-based protocol management and sharing
  • Automatic storage and retrieval of assay templates
  • System health diagnostics and usage monitoring
  • Cross-site data synchronization for multi-lab workflows
  • Regulatory-compliant cloud infrastructure
  • Simultaneous measurement of OCR and ECAR in live cells
  • Real-time profiling of glycolysis and mitochondrial respiration
  • Compatible with adherent and suspension cell lines
  • Multi-injection assay design for dynamic cellular response tracking
  • High-throughput analysis using 24- and 96-well formats
  • Intuitive workflow with guided assay setup and auto-calibration
  • Label-free technology preserving cellular integrity
  • Compatible with most microplate readers and imaging systems
  • Seamless integration with third-party liquid handlers
  • Supports assay customization with plug-in reagent kits
  • Export-ready data formats for GraphPad, Prism, Excel, and ELNs
  • Cross-compatible with thermal cyclers and incubators
  • Enables early identification of drug-induced mitochondrial toxicity
  • Facilitates metabolic phenotyping for cancer and immunotherapy research
  • Reduces hands-on time with automated calibration and injection steps
  • Provides reproducible, high-resolution insights into energy metabolism
  • Optimizes cell health monitoring in regenerative medicine and cell therapy
  • Cancer cell metabolism and tumor microenvironment profiling
  • Immunometabolism in T-cells, macrophages, and dendritic cells
  • Mitochondrial stress tests and ATP production rate assessment
  • Neurodegenerative disease modeling
  • Cellular respiration in microbiology and yeast studies
  • Nutrient dependency and metabolic adaptation studies
  • Pharmaceutical and Biotech R&D
  • Academic and Government Research Institutions
  • CROs and Drug Screening Facilities
  • Cancer and Immunology Labs
  • Metabolic Disease and Diabetes Research Centers
  • Regenerative Medicine and Cell Therapy Facilities
  • U.S. FDA 21 CFR Part 11
  • U.S. ISO 13485:2016
  • U.S. CLIA
  • Canadian Medical Devices Regulations (CMDR)

Case Studies

U.S. Biotech (Massachusetts)

A Massachusetts-based biotech firm used our Seahorse XF analyzer with customized metabolic flux kits to screen compound libraries for mitochondrial toxicity. Their workflow improved assay reproducibility and reduced discovery timelines by 35%.

U.S. Cancer Research Institute (Texas)

A cancer research group in Texas utilized our multi-sensor XF plates and real-time analysis modules to study immunotherapeutic targets in T-cells. The resulting OCR/ECAR profiles led to two successful grant-funded projects.

Canadian Academic Lab (British Columbia)

A university lab in British Columbia integrated our XF systems to investigate neurodegenerative disease models. Combining XF analyzers with our modular housings and Device Edge processors enabled reproducible, cross-batch metabolic profiling.

Contact Us

For custom-configured Seahorse XF analyzer systems, product guidance, or expert consultation, Physi Analytica is here to help. Whether you’re conducting pharmaceutical R&D or cellular energy studies, we provide the tools and support you need.Contact us today for technical assistance, product inquiries, or tailored solutions.

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