High-Performance SPR Systems for Biomolecular Interaction Analysis
Delivering accurate, label-free kinetic and affinity measurements
with reliable SPR platforms for modern B2B laboratories.
Advanced Surface Plasmon Resonance (SPR) Systems for Molecular Analysis
Surface Plasmon Resonance (SPR) is a powerful optical technique used to monitor real-time biomolecular interactions without the need for labels. Widely adopted in fields such as drug discovery, antibody development, and biosensor design, SPR enables researchers to quantify binding kinetics, affinity, and specificity with unmatched precision. Its ability to measure molecular interactions under near-physiological conditions makes it a critical tool in modern research and quality control environments.
Physi Analytica offers a portfolio of SPR solutions built for demanding B2B applications across North America. Our SPR systems are engineered for performance, reliability, and compliance—empowering users with rapid insights into molecular behavior. With a foundation in robust hardware and backed by a dedicated support team, we enable our customers to achieve consistent, reproducible outcomes in every application.
Core Components of SPR Systems
In addition to offering products and systems developed by our team and trusted partners for Surface Plasmon Resonance (SPR), we are proud to carry top-tier technologies from Global Advanced Operations Tek Inc. (GAO Tek Inc.) and Global Advanced Operations RFID Inc. (GAO RFID Inc.). These reliable, high-quality products and systems enhance our ability to deliver comprehensive technologies, integrations, and services you can trust. Where relevant, we have provided direct links to select products and systems from GAO Tek Inc. And GAO RFID Inc.
Core Components of SPR Systems
Hardware
High-precision sensors: optical, electrochemical, infrared are integrated with Optical & Imaging Sensors to ensure ultra-sensitive detection of biomolecular interactions during SPR analysis.
Embedded processors: AI chipsets are powered by Device Edge computing modules, enabling on-site real-time processing and kinetic modelling for SPR assays.
Modular housings for environmental protection: They are designed using ruggedized LoRaWAN End Devices, ensuring durable SPR operation even in demanding lab or field environments.
Data acquisition modules: built-in calibration features are enhanced through Z-Wave Gateways/Hubs allowing seamless signal transmission and synchronized data logging across SPR platforms.
Wireless and Ethernet-enabled communication: ports are supported with BLE Gateways, Beacons & Accessories, optimizing both short-range and cloud-connected SPR data sharing.
Software
- Intuitive graphical interfaces for assay design and execution
- Real-time sensorgram visualization and data analytics
- Automated kinetic fitting and affinity calculations
- User access controls and digital compliance logging (21 CFR Part 11 ready)
- Compatibility with LIMS and audit-trail systems.
Cloud Services
- Centralized data archiving with controlled access
- Remote experiment monitoring with alert systems
- AI-based interaction profiling and pattern recognition
- Role-based user dashboards for global team collaboration
- Long-term encrypted storage for regulatory audits.
Key Features and Functionalities
- Label-free detection with high sensitivity and reproducibility
- Ability to measure association and dissociation rates
- Multiplexing and high-throughput screening capabilities
- User-customizable surface chemistries and assay formats
- Compatibility with small molecules, proteins, antibodies, nucleic acids, and more
Integrations and Compatibility
- Seamless integration with automated liquid handling systems
- Plug-and-play compatibility with lab informatics tools (LIMS, ELNs)
- Data export in standard formats (CSV, XML, JSON, PDF)
- Cross-platform desktop and cloud access for remote analysis
- Support for standard biosensor chip formats and disposable cartridges
Benefits
- Rapid turnaround time for kinetic assays
- Eliminates the need for fluorescence or radioactive labels
- Reduces cost of reagents and consumables
- Enables early hit validation in drug discovery pipelines
- Enhances reproducibility in regulated environments
Applications
- Drug–target interaction studies
- Epitope mapping and antibody characterization
- Small molecule screening and fragment-based discovery
- Protein–protein and protein–nucleic acid interaction analysis
- Quality control and stability testing of biologics
Industries Served
- Pharmaceutical and Biotech R&D
- Academic and Translational Research
- Contract Research Organizations (CROs)
- Clinical Diagnostics and Biomarker Validation
- Biosensor Development and Nanotechnology
- Relevant U.S. & Canadian Standards
- 21 CFR Part 11 (FDA)
- USP <1058> Analytical Instrument Qualification
- ISO/IEC 17025
- Health Canada GLP Guidelines
- CLSI M23 Performance Standards for Antimicrobial Susceptibility Testing
Relevant U.S. & Canadian Standards
- FDA 21 CFR Part 11
- GLP / GxP (U.S. & Health Canada, OECD-compliant)
- ISO/IEC 17025
- PIPEDA / HIPAA
- USP General Chapter <1058>
Case Studies
United States (Pharmaceutical R&D)
A major U.S. pharmaceutical company adopted our SPR platform for screening drug candidates targeting protein–protein interactions. Integration with their LIMS enabled seamless data transfer and accelerated their hit-to-lead timeline by 30%.
United States (Biotech CRO)
A contract research organization specializing in antibody development used Physi Analytica’ SPR solutions to validate affinity maturation. Our platform provided consistent reproducibility across multiple assay types, increasing client retention.
Canada (Government Research Lab)
A Canadian governmental biosafety research institute deployed our SPR systems to investigate viral spike protein interactions. With remote monitoring and data centralization, teams across provinces collaborated on national health initiatives in real time.
Contact Us
Looking to integrate SPR into your analytical workflows?
Contact us for product guidance, demos, or implementation support. We’re ready to assist your lab with world-class solutions and expert service. for product guidance, demos, or implementation support. We’re ready to assist your lab with world-class solutions and expert service.